Frequently Asked Questions
All you need to know about our research, stem cells & therapy protocol.
All you need to know about our research, stem cells & therapy protocol.
MSCs have shown potential in nerve repair through their ability to release neurotrophic factors, support axonal growth, and modulate the inflammatory response in the nervous system.
Yes, MSCs are utilized in regenerative medicine due to their regenerative and immunomodulatory properties.
There isn’t a strict age limit, but the efficacy of MSC therapy might vary depending on factors like the patient’s age, overall health, and the specific condition being treated.
Limitations include maintaining MSC properties during prolonged culture, potential loss of potency with passaging, genetic instability, and ensuring scalability without compromising quality.
Common side effects may include fever, pain at the injection site, or mild immune reactions. Severe adverse effects are rare but can include infections or allergic reactions.
Yes, there can be variations in efficacy based on the tissue source of MSCs, influencing factors like proliferation rate, differentiation potential, and secretory profile.
Yes, various tissues such as bone marrow, adipose tissue, umbilical cord tissue, and dental pulp are sources of MSCs.
Ethical concerns mainly revolve around issues related to donor consent, the commercialization of stem cell therapies, and ensuring responsible and ethical use in research and treatment.
Some studies suggest subtle differences in MSCs from males and females, including variations in proliferation rates and differentiation potentials, but further research is needed to clarify these differences.
Limitations include variability in MSC characteristics based on tissue source, challenges in standardizing protocols for therapy, potential immune rejection in allogeneic treatments, and incomplete understanding of long-term effects.
Some studies suggest lifestyle factors such as exercise, certain diets, and specific medications may influence the body’s MSC production, but further research is needed to establish reliable methods for naturally increasing MSC production.
Yes, ongoing debates focus on standardization of protocols, long-term safety, efficacy across different conditions, and ethical considerations regarding commercialization and regulation.
Yes, numerous ongoing studies explore MSCs in various fields, including regenerative medicine, autoimmune diseases, neurological disorders, and cancer therapy, among others.
While generally considered safe, risks associated with MSC therapy might include immune reactions, infection, potential for uncontrolled cell growth, and limited long-term data on safety.
Yes, MSCs from different tissues may exhibit variations in their proliferation rate, differentiation potential, and the types and quantities of growth factors they secrete.
Yes, MSC therapy is being explored and used in orthopedic conditions such as osteoarthritis, tendon injuries, and cartilage defects due to their regenerative properties.
MSC therapy is being investigated for skin conditions due to their potential in promoting wound healing, tissue regeneration, and reducing inflammation in conditions like chronic ulcers.
Yes, MSC therapy is used in veterinary medicine for various conditions including orthopedic injuries, osteoarthritis, tendon and ligament injuries, and certain immune-mediated diseases in animals.
Yes, MSCs can be stored in specialized stem cell banks for potential future therapeutic use.
Yes, MSCs can be genetically modified in laboratory settings to enhance certain characteristics or to express specific genes for therapeutic purposes.
Yes, MSCs can be genetically modified to express specific genes, making them a potential carrier for gene therapy delivery due to their migratory and immunomodulatory properties.
Yes, MSCs can be combined with various therapies such as drugs, growth factors, or scaffolds to enhance their effectiveness in tissue repair and regeneration.
MSCs have shown promise in preclinical studies for spinal cord injuries by promoting tissue repair, reducing inflammation, and supporting axonal regeneration.
Yes, MSCs are being investigated for their potential in osteoporosis treatment by promoting bone formation through osteogenic differentiation and secretion of factors that enhance bone regeneration.
Yes, MSCs have shown potential in treating autoimmune diseases due to their immunomodulatory effects, which help regulate the immune response and reduce inflammation associated with these conditions.
Yes, they can differentiate into bone cells (osteocytes), cartilage cells (chondrocytes), fat cells (adipocytes), and other cell types.
MSCs show potential in diabetes treatment by promoting pancreatic regeneration, reducing inflammation, and modulating the immune system, but more research is needed for clinical application.
MSCs have shown promise in preclinical studies for liver diseases due to their ability to modulate inflammation, promote tissue repair, and support liver regeneration.
MSCs show potential in neurological disorders due to their ability to promote neural tissue repair, modulate inflammation, and support neural cell survival and regeneration.
While MSCs have shown the ability to promote tissue repair and regeneration, complete regeneration of damaged tissues may depend on various factors, including the extent of damage and the microenvironment.
MSCs have shown promise in heart-related conditions by promoting tissue repair, angiogenesis, reducing inflammation, and potentially improving heart function in preclinical and early clinical studies.
MSCs are being researched for lung diseases due to their anti-inflammatory and regenerative properties. They show potential in conditions like pulmonary fibrosis and acute respiratory distress syndrome (ARDS).
Yes, MSCs possess immunomodulatory properties, influencing immune responses by regulating the activity of immune cells, reducing inflammation, and modulating the immune system’s overall function.
Studies suggest that MSCs can modulate the gut microbiome indirectly by influencing immune responses, reducing inflammation, and promoting intestinal barrier integrity.
MSCs can be administered via various routes including intravenous infusion, intra-articular injection, or directly into the affected tissue or organ depending on the condition being treated.
MSCs are isolated from tissues like bone marrow or adipose tissue, then cultured and expanded in laboratory settings under specific conditions.
Regulatory agencies like the FDA oversee MSC-based therapies, ensuring safety, efficacy, and quality control through rigorous evaluation and approval processes.
Environmental factors like oxygen levels, growth factors, and culture conditions significantly impact MSC behavior, affecting their proliferation, differentiation, and therapeutic potential.
Unlike embryonic stem cells, MSCs are multipotent (can differentiate into limited cell types) and are found in adult tissues.
MSCs regulate the immune system by suppressing excessive immune responses, modulating immune cell activity, and secreting factors that induce immune tolerance and reduce inflammation.
MSCs contribute to wound healing by releasing growth factors and cytokines that stimulate cell proliferation, angiogenesis (new blood vessel formation), and modulate the immune response.
With age, MSCs show decreased proliferation and differentiation potential, altered gene expression, and reduced regenerative capacity, impacting their effectiveness in tissue repair.
MSC therapy has shown promise in various clinical trials, demonstrating effectiveness in conditions like graft-versus-host disease, cartilage repair, and some autoimmune disorders. However, further studies are ongoing to establish efficacy conclusively.
MSCs are a type of adult stem cell found in various tissues in the body, capable of differentiating into several cell types, such as bone, cartilage, and fat cells.
Challenges involve maintaining cell purity, scalability of production without compromising quality, ensuring consistency between batches, and complying with regulatory standards for large-scale manufacturing.
Costs can vary widely based on factors like the source of MSCs, processing methods, administration routes, and the specific condition being treated. Expenses include cell isolation, culture, storage, and treatment administration.
MSC therapy holds potential in chronic pain management by modulating inflammation, promoting tissue repair, and releasing factors that can reduce pain signaling pathways.
Ethical considerations involve issues related to tissue donation, patient consent, potential for misuse or commercialization, and ensuring research complies with ethical guidelines set by regulatory bodies.
Common markers include CD73, CD90, and CD105, while lacking hematopoietic lineage markers such as CD45 and CD34. Additionally, MSCs typically express markers like STRO-1 and SSEA-4.
Potential applications include regenerative medicine, treating orthopedic injuries, autoimmune diseases, and more.
MSCs need to be stored in cryopreservation at very low temperatures, typically in liquid nitrogen, to maintain viability and functionality for future use.
MSCs hold promise in treating various conditions, including orthopedic injuries, autoimmune disorders, cardiovascular diseases, neurodegenerative conditions, and more.
Autologous therapy uses a patient’s own MSCs, harvested and re-administered back to the same individual. Allogeneic therapy involves using MSCs from a donor source, which can be a different individual.
Inflammatory environments can alter MSC behavior, prompting them to release anti-inflammatory factors and alter their secretome, affecting their immunomodulatory properties and regenerative potential.
MSCs play a key role in tissue repair, immune regulation, and modulation of the microenvironment in which they reside.
MSCs act through various mechanisms, including differentiation into specialized cells, secretion of growth factors and cytokines, immune regulation, and tissue repair support.
MSCs have a dual role in cancer; they can home to tumors and promote tumor growth in some contexts, but they’re also being studied for their potential in delivering anti-cancer agents and modulating the tumor microenvironment.
MSCs contribute to tissue repair by differentiating into specialized cells and releasing factors that promote cell growth, modulate inflammation, and enhance tissue regeneration.
They are found in various tissues like bone marrow, adipose (fat) tissue, umbilical cord tissue, dental pulp, and others.